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Tel: 859-242-7836

Non-GLP Options

Not every patient is a candidate for GLP-1 therapy — and not everyone needs an injection to achieve results.


Our clinic offers a variety of clinically proven oral and combination medications to help manage appetite, boost metabolism, and support sustainable weight loss under medical supervision.

When Non-GLP Options Make Sense

Non-GLP-1 medications may be right for you if:

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  • You prefer oral therapy over injections.

  • You have mild to moderate weight loss goals or want to avoid gastrointestinal side effects.

  • GLP-1 medications are not medically appropriate (e.g., certain thyroid conditions or GI sensitivities).

  • You’re seeking an affordable or insurance-covered alternative for weight management.

Spilled prescription pills
Woman using weight scale

Oral & Combination Options

All medications are prescribed after a telehealth evaluation with a licensed provider and individualized to your health profile.

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1. Contrave® (Bupropion/Naltrexone)

An FDA-approved combination that acts on the brain’s hunger and reward centers to reduce cravings and emotional eating.

  • May improve energy and mood

  • Common side effects: mild nausea, headache, insomnia

2. Qsymia® (Phentermine/Topiramate)

Combines a low dose stimulant (phentermine) with topiramate to reduce appetite and increase satiety.

  • Effective for moderate to significant weight loss

  • May also improve blood sugar and cholesterol levels

3. Phentermine (Monotherapy)

A short-term appetite suppressant used for jump-starting weight loss under close medical supervision.

  • Typically prescribed for up to 12 weeks

  • Works best alongside diet and exercise changes

4. Metformin

Originally used for blood sugar regulation, metformin can improve insulin sensitivity and support modest weight reduction.

  • Often used in metabolic syndrome, insulin resistance, or PCOS

  • Well-tolerated and may reduce appetite

5. Topiramate

Used off-label for appetite control and binge eating reduction.

  • May be prescribed alone or with other medications

  • Can help patients who experience nighttime or stress-related eating

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